FORMULATION AND EVALUATION OF CONTROLLED RELEASE FLOATING TABLETS OF CEFIXIME USING HYDROPHILIC POLYMERS
نویسندگان
چکیده
منابع مشابه
Formulation, Evaluation and Study of Effect of Hydrophilic Polymers on Release Rate of Cefixime Floating Tablets
Floating matrix tablets of cefixime trihydrate were developed to prolong gastric residence time and to increase drug absorption and hence bioavailability. Hydrophilic polymers viz. HPMC K4M and Xanthan gum were incorporated in varied proportions to develop floating matrix tablets of cefixime by direct compression method. Buoyancy was achieved by adding an effervescent mixture of sodium bicarbon...
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In view of the circadian rhythm of cardiovascular diseases, a delayed-onset extended-release (DOER) formulation of metoprolol tartrate (MT) was prepared. This was achieved through dissolution-guided optimization of the proportion of Methocel K4M and Methocel K15M. Core erosion ratio was greater than 50 %, thereby showing steady release of the drug after the lag time until complete dissolution. ...
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Objective: Ofloxacin is a synthetic chemotherapeutic antibiotic of the fluoroquinolone drug class considered to be a second generation fluoroquinolone. Ofloxacin is a broad-spectrum antibiotic that is active against both Gram positive and Gram negative bacteria. The aim of the present study is to control the release Ofloxacin by formulating a tablet using the natural polymer likes Aloes powder ...
متن کاملHydrophilic Natural Polymers for Sustained-controlled Release of Calcium Hydroxide
Calcium Hydroxide (CH) is commonly employed as intracanal medicament in endodontics. In order to maximize its therapeutic effects, it is essential to develop new approaches for preparing the controlled drug release systems which, in turn, facilities the dissociation of CH into calcium and hydroxyl ions. This work studies the sustained-controlled release of calcium ions and the effect of pH chan...
متن کاملHydrophilic Natural Polymers for Sustained-controlled Release of Calcium Hydroxide
Calcium Hydroxide (CH) is commonly employed as intracanal medicament in endodontics. In order to maximize its therapeutic effects, it is essential to develop new approaches for preparing the controlled drug release systems which, in turn, facilities the dissociation of CH into calcium and hydroxyl ions. This work studies the sustained-controlled release of calcium ions and the effect of pH chan...
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ژورنال
عنوان ژورنال: International Research Journal Of Pharmacy
سال: 2019
ISSN: 2230-8407
DOI: 10.7897/2230-8407.100129